Dermatol. vol no.4 supl.1 Rio de Janeiro July/Aug. Two male patients diagnosed with Zoon’s plasma cell balanitis, confirmed by biopsy, were subjected to. In , JJ Zoon first recognized balanitis circumscripta plasmacellularis (plasma cell balanitis) as an idiopathic, rare, benign penile dermatosis. Balanitis is inflammation of the glans penis. When the foreskin is also affected, it is termed Zoon’s balanitis also known as Balanitis Circumscripta Plasmacellularis or plasma cell balanitis (PCB) is Albertini JG, Holck DE, Farley MF ().

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At a Glance – Lichen sclerosus versus Zoon’s balanitis

Sites affected It is most commonly located on the glans penis, but inner surface of balanitie and coronal sulcus may be involved. From Wikipedia, the free encyclopedia. CS1 Spanish-language sources es Infobox medical condition new Articles containing Greek-language text Articles with references in external links Commons category link is on Wikidata. J Dermatol Surg Oncol.

Zoon balanitis: A comprehensive review

Promotion of good hygiene is an easy and potentially beneficial measure. Nikolowski W, Wiehl R. Complete resolution of Zoon balanitis with photodynamic therapy — A new therapeutic option?

Erythroplasia of the female genitalia. Siderophages and extravasated red blood cells.


Histologically, the process begins with a slight thickening of the epidermis, with parakeratosis and a characteristic band-like lymphocytic infiltrate of rare plasma cells in the upper dermis. This article has been cited by other articles in PMC.

Balanitis – Wikipedia

These are more common in cases with a dense infiltrate. Plasma cell balani tis of Zoon treated successfully with topical tacrolimus.

A dermatological examination indicated the presence of three shiny, well-defined, reddish plaques on the glans and foreskin Figure 1. A number of predisposing factors proposed are nevertheless unproven: According to the European guidelines for management of balanoposthitis, the definitive treatment of ZB is:.

Occasional potential for malignant change. Although it was described by Zoon inits etiopathogenesis still remains hypothetical. Management Diagnosis confirmed by skin biopsy. We report the use of pimecrolimus, a soon of tacrolimus, with good response.

Surabhi Dayal and Priyadarshini Sahu. In addition, other possible causes of ZB balantis have been described in the literature include chronic infection with Mycobacterium smegmatis and human papillomaviruses HPV.

Zoon’s plasma cell balanitis: a report of two cases treated with pimecrolimus

Topical application of the immunosuppressant tacrolimus accelerates carcinogenesis in mouse skin. Mahajan BB, Mehta V. Arch Klin Exp Dermatol. ZB is an entity of utmost importance both for the patients due to their concern regarding its prognosis and its management can be really challenging for the dermato-venereologists.


Zoon’s plasma cell balanitis balanitis circumscripta plasmacellularis Diagnosis requires skin biopsy. J Cutan Med Surg. In dogsbalanoposthitis is caused by a disruption in the integumentary systemsuch as a wound or intrusion of a foreign body.

As far as Indian literature is concerned, there are no published data regarding the incidence and prevalence of ZB in Indian patients. It is a benign condition of unknown etiology that tends to be asymptomatic. Dr Bawa-Garba’s suspension extended by six months following case review Dr Hadiza Bawa-Garba’s suspension from the medical register has been extended for Although it is described as benign in nature, its association with premalignant conditions such as erythroplasia of Queyrat really puts the clinician in a great dilemma.

A sclerotic white ring at the tip of the prepuce is diagnostic. National Center for Biotechnology InformationU. Balanoposthitis is believed to have contributed to the decline to near-extinction of Gilbert’s potoroo. Some authors have also suggested that aseptic technique applied during circumcision, followed by regular cleaning during healing, might lead to improvement of the condition.